Becoming the highest ever ranking Chinese national in any United Nations post, Dr Margaret Chan has taken office as Director-General of the World Health Organization.

"I want my leadership to be judged by the impact of our work on the health of two populations: women and the people of Africa," Dr Chan said. "WHO has a long history of commitment to those in greatest need, including the most vulnerable groups."

Dr Chan has set out six priority areas on which she intends to focus the work of WHO: development for health, health security, building the capacity of health systems, developing better information and knowledge, enhancing partnerships and improving the performance of the Organization.

Speaking to staff, Dr Chan said that the priorities she has emphasized during and since her election will not mean a major restructuring of WHO. She said she would be looking for ways in which different parts of the Organization can work better together. She told staff, "I will stick with my promise. Reform, yes. Upheaval, no."

She took the opportunity to praise the work of Dr Anders Nordstrom, who has been acting Director-General since the sudden death of the former Director-General, Dr Lee Jong wook, in May 2006.

Dr Chan was appointed by the World Health Assembly in November 2006. Her term of office will run until June 30, 2012.

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